Which leukocytes are typically considered agranular?

Which leukocytes are typically considered agranular?

• A. Neutrophils and Eosinophils
• B. Monocytes and Lymphocytes
• C. Basophils only
• D. Platelets

Answer: (B)

Leukocytes are grouped as granular or agranular based on whether their cytoplasm shows visible granules with standard staining. Agranular leukocytes including monocytes and lymphocytes lack conspicuous cytoplasmic granules, making them distinct from the granular types—neutrophils, eosinophils, and basophils—which do show obvious granules. Platelets aren’t leukocytes at all; they’re small cell fragments derived from megakaryocytes. So, the best answer is monocytes and lymphocytes because they are the leukocytes that are typically agranular.

Leukocytes are grouped as granular or agranular based on whether their cytoplasm shows visible granules with standard staining. Agranular leukocytes including monocytes and lymphocytes lack conspicuous cytoplasmic granules, making them distinct from the granular types—neutrophils, eosinophils, and basophils—which do show obvious granules. Platelets aren’t leukocytes at all; they’re small cell fragments derived from megakaryocytes. So, the best answer is monocytes and lymphocytes because they are the leukocytes that are typically agranular.